Refugees also headed to Europe, with Germany currently home to more than 850,000 people who fledSyria.
Leaders around the world are following the fast evolving situation.
President Biden said he was closely monitoring the events in Syria and was in constant touch with regional partners.
Bullet-riddled portrait of Syrian President Bashar al-Assad in city of Hama as rebels advanced this weekOMAR HAJ KADOUR/AFP via Getty Images