Kennedy was confirmed 52-48, with Sen. Mitch McConnell (R-KY) joining with all Democrats in opposition.

Kennedy was confirmed despite pleas from his cousin, Caroline Kennedy, to reject him.

That included a 2023 podcast interview in which Kennedy said that no vaccine is safe and effective.

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Robert Kennedy Jr.Photo by Ricky Carioti/The Washington Post via Getty Images

But Kennedy said that he meant to add that no vaccine was safe for every person.

In a statement, McConnell noted that he was a survivor of childhood polio.

Donald Trump and ABC News' Terry Moran