Oscar-winner Murphy is returning to the iconic role of Tommy Shelby, leader of the eponymous Birmingham gangster family.
Production on the feature will begin before the year is out.
He will produce alongside Caryn Mandabach, Murphy and Guy Heeley.
L-R: Tim Roth, Cillian Murphy, Barry Keoghan and Rebecca FergusonMichael Buckner for Deadline/Getty/Marco Grob/Universal Pictures
Exec producers include Harper, David Kosse, Jamie Glazebrook, Andrew Warren and David Mason.
The movie will be made in association with BBC Film.
Roth secured a Best Supporting Actor nomination for 1995sRob Roy.
He is represented by CAA, Jackoway Tyerman Wertheimer, and Markham, Froggatt & Irwin.