Donald Trump Removes Doug Emhoff And Other Joe Biden Appointees From U.S. Stephen Colbert: This is a very different place.

Today they announced two board members, Bashar-al-Assad and Skeletor.

Sarah Silverman: I just really miss the days when you were Americas only orange asshole.

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Cindy Mizelle, Conan O' Brien and Ada, Sandler at the Mark Twain Prize ceremony.Clifton Prescod for Netflix

Nikki Glaser found herself stopped by a recurring character on OBriens show, the obnoxious man called The Interrupter.

Dont you have… Glaser said.

A cabinet meeting to get to?

Donald Trump in Michigan today.

Great, so you are the new… she asked.

Secretary of Housing and Urban Development, he answered.

You are also a… she said, before he added, Registered sex offender.

Which this administration considers… Glaser said, before The Interrupter quickly responded, A massive plus!

Netflix will stream the special later this year.

Other comedians didnt directly address Trump, but surely referred to the political environment.

This is a fitting introduction to America.

Nothing represents America better than an unbelievably powerful predator pleasuring himself on television.

Bill Burr said, Nothing says comedy like the free-flowing creative vibes of the District of Columbia.

I dont know what it is.

I lost Wifi in January …

The quip got laughs.

My eternal thanks for their selfless devotion to the arts.

His comment drew a long, sustained ovation.

The implied comparison was to the current moment.

Twain was allergic to hypocrisy and he loathed racism, OBrien noted.

Above all, Twain was a patriot in the best sense of the word.

He loved America but knew it was deeply flawed.

OBrien couldnt finish on a serious note, though.

After a standing ovation for his remarks, he announced another guest.

They were soon joined by other Mark Twains who exchanged hugs, to a sentimental soundtrack.